Director, BK21 FOUR Program Professor
Department of Biothechnology, College of Biomedical and Health Science, Konkuk University, GLOCAL Campus.
Phone: 010-3460-1015, Email: choidk@kku.ac.kr
Research Interest
1. Developments in the inhibitors of neuroinflammation and neurodegeneration
2. The mechanisms of neuronal loss in neurodegenerative disease
3. Cognitive rehabilitation of memory against cognitive impairment in animal model
Ameliorative potential of desalted Salicornia europaea L. extract in multifaceted Alzheimer’s-like scopolamine-induced amnesic mice model. Scientific reports 8 (1), 1-16
The Neuroprotective Effects of GPR4 Inhibition through the Attenuation of Caspase Mediated Apoptotic Cell Death in an MPTP Induced Mouse Model of Parkinson’s Disease. International Journal of Molecular Sciences 22 (9), 4674
α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease. Neuropharmacology 97, 46-57
Biography
Dong-Kug Choi is a Professor at the Department of Biotechnology, Konkuk University, Korea. He has received PhD 1999 in molecular medicine at the Human Genome Ctr., University of Tokyo, and did his postdoctoral training at Columbia University and Cornell University, New York, 2004. He is currently professor at the department of biotechnology, Konkuk University, Korea. He has served several positions including Chair of the Department of Biotechnology and the Vice-President position for Industry and Academic Research Affairs at GLOCAL campus, Konkuk University, Korea. He has more than 180 peer reviewed research articles including Nature, PNAS, Journal of Neuroscience etc. He is serving as an Editorial Board Member of scientific journals such as American Journal of Molecular Biology, International Journal of Neurology Research. His laboratory investigates molecular mechanisms of neuroinflammation and neuronal cell death. Currently, Choi's group works on the role of different receptors such as the Nuclear receptors, G-Protein coupled receptors and Glutamate receptors, as the therapeutic target for neurodegenerative diseases. His team utilized cell culture models, transgenic animal models, and neurotoxic agent-induced animal models. To develop neuroprotective agents, Choi's team investigates natural and chemical compounds that show the anti-neuroinflammatory property or cognition (memory) enhancing activity. Overall, finding therapeutic targets and molecules for treating neurodegenerative disease based on the pathophysiological and pharmacological correlation are major research interests of Prof. Choi.
