Assistant Professor
Lab. of Immunology, Department of Biotechnology, College of Biomedical and Health Science, Konkuk University GLOCAL Campus (2011 ~ present)
Phone: +82-43-840-3904, Email: kangtbko@kku.ac.kr
Education and Training
· Post-doctoral research associate: Depart. of Biol. Chem., Weizmann Institute of Science, ISRAEL
· Ph.D. in Immunology: Konkuk University, Korea
· M.S. in Animal Product: Konkuk University, Korea
· B.S. in Animal product: Konkuk University, Korea
Research Interest
· Signaling for inflammasome: signaling molecules, regulation, and related diseases
· Signaling for programmed cell death: apoptosis and necroptosis in health and diseases
Selected publications
Kim TY, Kang JH, Lee SB, Kang TB, Lee KH. Down-regulation of pro-necroptotic molecules blunts necroptosis during myogenesis (2021). Biochem Biophys Res Commun. 557:33-39.
Jiang J, Sun X, Akther M, Lian ML, Quan LH, Koppula S, Han JH, Kopalli SR, Kang TB, Lee KH. Ginsenoside metabolite 20(S)-protopanaxatriol from Panax ginseng attenuates inflammation-mediated NLRP3 inflammasome activation (2020). J Ethnopharmacol. 251:112564.
In EJ, Lee Y, Koppula S, Kim TY, Han JH, Lee KH, Kang TB. Identification and Characterization of NTB451 as a Potential Inhibitor of Necroptosis (2018). Molecules. 23(11):2884.
Wallach D, Kang TB. Programmed Cell Death in Immune Defense: Knowledge and Presumptions (2018). Immunity. 49(1):19-32.
Kang TB, Jeong JS, Yang SH, Kovalenko A, Wallach D. Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3(2018). Cell Death Differ. 25(6):1107-1117.
Wallach D, Kang TB, Dillon CP, Green DR. Programmed necrosis in inflammation: Toward identification of the effector molecules (2016). Science. 1;352(6281):aaf2154.
Kang TB, Yang SH, Toth B, Kovalenko A, Wallach D. Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity. 2013 38(1):27-40.
